wellbutrin

Not Even Once

Is Flakka as Dangerous as it Sounds on the News?

Yes and no, but mostly yes. Let’s start with what exactly flakka is. Flakka is alpha-pyrrolidinovalerophenone, but let’s call it A-PVP. A-PVP is a cathinone. Flakka is a Schedule I Controlled Substance under Florida Statute Chapter 893.03 which means that there is no currently accepted medical use for it and the potential for abuse is high. It is also a Schedule I controlled substance on the Federal Register which has essentially the same criteria. The terms A-PVP and flakka will be used interchangeably throughout.

Disclaimer:

There are some of you who may read this and can speak nerd/science jargon better than I can. Not many, but some. You will inevitable go back onto a drug bulletin board saying that I don’t know what I am talking about and spreading misinformation, we should be having a consultation. Delivering information that it not hyper-analytical so it can be processed by the public is neither ignorant or misleading. While this might not be PhD level chemistry or pharmacology information, it was not intended to be. The only point I am trying to get across is DON’T USE THIS CRAP!

Misinformation on Flakka

The only stories that you hear on the news are the truly bizarre incidents. So keep in mind that the local news only shows stories that sensationalize the topic. You will never hear “BREAKING NEWS AT 6 O’CLOCK! High School Student Kevin Smokes Flakka and Says it was Pretty Cool, but Wouldn’t do it Again!” Instead you will hear “BREAKING NEWS AT 6 O’CLOCK! MAN ON $5 DRUG THAT CAUSES INSTANT INSANITY IMPALES NUTSACK ON FENCE POST! ZOMBIE APOCALYPSE IS UPON US!”

Flakka and the current flakka hysteria is similar to bath salts and how bath salts were viewed and portrayed just a few years ago. Remember when bath salts were going to turn people into flesh eating zombies? There was the Miami cannibal attack that turned out to be a case of “this dude is crazy” rather than bath salt intoxication? Yet, that didn’t stop the bath salt hysteria. There is also my personal favorite, a man in Pennsylvania got out of his car, ran down the street into an occupied residence(thereby committing a felony), was chased out of said house and jumped onto a police car causing damage to the police vehicle. Why? Because he was high on bath salts, believed his car was melting and that he was being chased by electricity.

So enjoy the news for what it is. It is not an accurate depiction of the ordinary experience. Watch this video and take a look at the recent “newsworthy” flakka incidents in South Florida.

The Sun-Sentinel is an extremely reputable and reliable news source in South Florida. What did it show? A guy running naked in the middle of an intersection, a guy trying to break into the police department, a guy diving over a spiked fence with no regard for the safety of his testicles, some guy running around naked on his roof and some truly despicable person that attacked an old lady in her home when he was high. I’m not going to bother to look, but chances are that guy had a violent history to begin with. So the media’s portrayal of flakka is skewed.

Q: Ok, so if we are being mislead and Flakka isn’t that dangerous, it is OK to try it right?

Let’s Hear from Broward County Sheriff Scott Israel

“In my 36 years in law enforcement, I’ve never seen a drug this dangerous.”

Q: “I know, but he is the Sheriff and he has to say drugs are bad. Is he exaggerating?”

A: No. He is not. Flakka really is that bad.

Anybody who knows me knows that I wouldn’t say that if I didn’t truly believe it. I’ll spare everybody the speech on unregulated Chinese laboratories and quality control. The manufacturers appear to be doing a fantastic job. Make no mistake about it, I firmly believe that A-PVP and its predecessor MDPV are two of the most, if not the most, addictive substances on the face of the planet. While recovery from stimulant addiction is not nearly as debilitating as opiate addiction, the length of time from first use to addiction is faster. Cocaine is widely regarded as the drug with the quickest path to addiction. I disagree. In my experience concerning, flakka and MDPV, users go from experimenting to full blown addiction in a matter of days. While flakka won’t eat your skin away like homebrew desomorphine, it will still destroy your life. Quickly.

In order to understand why flakka is so dangerous you first need to understand the different types of commonly used recreational stimulants and how those stimulants affect your mind and your body. There are four(4) primary types of recreational stimulants. There is cocaine, amphetamines, methylphenidate and cathinone’s. Each of those classes has what are called analogs, isomers and/or derivatives which are structurally similar and have similar effects. We are going to ignore methylphenidate and its related compounds for this discussion. For some reason, there has never been much in the way of recreational use of cocaine analogs. However, they are freely available and, for the most part, are not scheduled controlled substances. For amphetamines there are different types of amphetamines such as methamphetamine, dextroamphetamie and 4F-amphetamine. There are literally hundreds of amphetamine analogs that are not scheduled and legally available. There is also a wide variety of substances that fall under the cathinone variety such as MDPV, BK-MDMA, Mephedrone, Methylone and even the antidepressant Wellbutrin. Some legal, some not.

How Stimulants Work

All stimulants work in essentially the same way. Stimulants increase the amount of three neurotransmitters in your brain. Those neurotransmitters are dopamine, serotonin and norepinephrine. Dopamine is believed to be the primary neurotransmitter affected by stimulants. Your body and mind associate dopamine with pleasure. The more dopamine that is present in your synapsis, the more pleasurable the activity. When you are taking part in a pleasurable activity your brain naturally releases more dopamine into your synapsis thereby making the experience pleasurable. As the pleasurable activity ceases to exist or ceases to take place the dopamine is reabsorbed and you go back to a normal mood.

When it comes to stimulants, there are two ways to increase the amount of dopamine in your synapsis. You can produce more thereby flooding the synapsis with dopamine. This is the way that amphetamines operate. Think of filling up a bucket with water. The bucket is the synapsis and the water is the dopamine. When you take methamphetamine, dextroamphetamine or any other type of amphetamine that chemical compound is telling your brain to pump more dopamine into the synapsis. (Note: I know that ALL amphetamines don’t necessarily act like this. Ecstasy is in the amphetamine class and it releases more serotonin than dopamine, but don’t be so picky and just humor me on this one.)

The second way to increase the amount of dopamine in your synapsis is by not allowing it to leave. Normally dopamine is released into the brain, does its job and is reabsorbed. Cocaine prevents dopamine from being reabsorbed. That makes cocaine a dopamine reuptake inhibitor. Cocaine will let dopamine in but will not let it out. Cocaine forces dopamine to remain in the synapsis and accumulate.

Synthetic Cathinones

There are numerous types of synthetic cathinones and not all of them work the same way. Certain synthetic cathinones, such as methylone, have a more serotogenic effect(huggy, kissy, cuddly) than a dopamine effect. However, the compounds related to pyrovalerone such as MDPV and A-PVP appear to focus primarily on dopamine and norepinephrine. The increase in norephinephrine is an important concern to law enforcement as norepinephrine provokes the “fight or flight” reaction in people. An increase in norepinephrine can lead to aggressive, hostile, violent behavior and purported acts of superhuman strength in agitated users.

Here is Why Flakka is so Dangerous

A-PVP, like its chemical cousin MDPV, acts as both a dopamine/norepinephrine release and reuptake inhibitor simultaneously. If using cocaine is compared to standing in a rainstorm for 15 minutes smoking A-PVP is the equivalent of standing and a thunderstorm for four hours. Flakka increases both dopamine and norepinephrine by pumping more dopamine and norepinephrine into the synapsis while at the same time preventing it from leaving. While cocaine is a short acting dopamine reuptake inhibitor, flakka is a longer acting reuptake inhibitor. While dopamine levels might not rise quite to the level that would be associated with cocaine use, the heightened levels of dompaine and norephinephrine, sustained for hours on end, can induce stimulant psychosis and negative physical side effects quickly. Due to the intensity of the drug, the compulsion to redose is extreme and tolerance develops very quickly. The prolonged heightened levels of norepinephrine quickly leads to increased heart rate, increase body temperature, grinding teeth and the other negative physical side effects. Onset of stimulant psychosis develops quickly due to several factors including, but not limited to, compulsive redosing, the sustained large amounts of dopamine in the synapsis and sustained high levels of norepinephrine resulting in decreased sleep. It is not uncommon to see stimulant psychosis appear within a matter of 2 days with MDPV or flakka.

This is a very basic overview. While you might not run down the street naked and get hung up on a fence by your crotch, even short term use can cause permanent neurological damage. If you are not familiar with the Montana Meth Project. Take a look at their videos. Same goes with flakka. Not even once.

For more information, please contact us at:

The Law Offices of Michael A. Dye, PA, 1 E Broward Blvd #700, Fort Lauderdale, FL 33301 (954)990-0525 or
The Law Offices of Michael A. Dye, PA, 2 S Biscayne Blvd, Miami, FL 33131 (305)459-3286

Who is Writing the DUI Laws?

Drugged driving has rapidly become an issue that has a significant impact on public safety. With 2015 just around the corner I am going to go out on a limb and make my drugged driving predictions for 2015.

My Conclusion:

At least one poorly drafted, overbroad and unconstitutional bill purportedly drafted to curb drugged driving will not make it through the legislature. To the public, that means no change.

Here is what history has taught us:

Florida Statute 316.193 is Florida’s DUI statute. For at least the last three years, there has been at least 1 bill introduced in the Florida Legislature which has attempted to redefine the crime of DUI. The majority of the proposed changes to Florida’s DUI statute have focused on drugged driving.

All 50 states have laws prohibiting driving while impaired by drugs. The differences between the various state statutes is a) which drugs and substances qualify as an “impairing substance” and b) the legal definition of “impairment.” Two recent attempts, Florida Senate Bill 1810, 2012 & Florida Senate Bill 1118, 2014 would have changed the definition of impairment, for drugged driving cases, from an “actual impairment” standard to a “per se” definition of impairment. A “per se” standard is also referred to as “metabolite DUI.”

Florida’s Current DUI Statute Requires Actual Impairment

Florida’s DUI statute permits an individual to be charged with and convicted for DUI under an alcohol or drug theory. With regard to drug impairment, under the current statute, an individual’s ability to drive a car must actually be impaired by a controlled substance while driving in order for the state to secure a conviction for DUI. The recent attempts to change Florida to a per se DUI state would have made it a crime to have any detectable amount of a controlled substance, a controlled substance analogue or a metabolite of a controlled substance while driving. The obvious benefit of creating a per se standard is that prosecutors do not have to prove actual impairment. Under a per se statute, a person can be convicted of DUI even if he was completely sober at the time he was driving but remember that there is a cosmetic surgeon performing nose surgery in New Jersey to help you. The number of people convicted of DUI will rise simply because a per se statute expands criminalizes what was previously lawful behavior.

The flawed logic behind a per se DUI statute is that a conviction equals justice. However, does convicting a sober individual of DUI truly amount to justice? How is the public good served by convicting a sober driver of DUI? Who are we trying to protect from the menace of sober drivers? Almost any politician would be glad to take responsibility for creating a law that lead to an increase in drugged driving convictions.

In a rush to be seen as “tough on crime” politicians throughout the country have proposed some of the worst legislation imaginable. Florida Senate Bill 1810, 2012 is pretty much the “gold standard” for poorly drafted legislation. The bill died in committee. I do not believe that Senator Stephen Wise, who proposed Senate Bill 1810, is ignorant or that the bill was in any way malicious. He recognized that there is a problem and tried to solve it. By taking an extremely broad approach to the problem of drugged driving, Senator Wise drafted a bill that would have created some unintended and otherwise comical results. Let’s look at some of the ridiculous results that would have arisen from a strict interpretation of Florida Senate Bill 1810 had it become law in 2012.

Proposed Statutory Amendments Expanding the Definition of Impairment:

FL Stat 316.193(1)(c): “The person has in the blood or urine a substance identified as a controlled substance as defined in Schedule I of chapter 893 or the Federal Register, or one of its metabolites or analogs;”

Florida Stat 316.193(1)(d): “The person has in the blood or urine a substance identified as a controlled substance in Schedule II, Schedule III, or Schedule IV of chapter or the Federal Register, or one of its metabolites or analogs.”

Proposed Statutory Amendments Creating New Affirmative Defenses

FL Stat 316.193(15)(a): “If a person who is charged with violating subsection (1)(d) introduced into his or her body a controlled substance prescribed by a licensed health professional authorized to prescribe the controlled substance and if the person consumed the controlled substance in accordance with the health professional’s directions, the person is entitled to an affirmative defense against any allegation that the person violated subsection (1)(d). The introduction of a non-prescribed substance into the person’s body does not constitute an affirmative defense with respect to any non-prescribed substance.”

FL Stat 316.193(15)(b): Except for paragraph (a), the fact that a person charged with violating subsection (1) is or was legally entitled to introduce into the human body alcohol, a chemical substance, a controlled substance, a medication, a drug, or any other impairing substance does not constitute a defense against any charge of violating subsection (1).

Absurd Results Created by Poorly Drafted Legislation:

Absurd Result # 1 DUI Marijuana

A chemotherapy patient who smokes 1 puff of marijuana for medicinal purposes and drives 10 days later will be guilty of DUI. Despite the fact he would no longer be impaired by marijuana, he would still be found guilty of a DUI because marijuana metabolites can be detected in biological fluid for up to one month. The patient is not entitled to either of the above listed affirmative defenses because marijuana is a Schedule I Controlled Substance at the state and federal level. If marijuana were to become legal in Florida, the same individual would still not have an affirmative defense due to marijuana remaining a Schedule I Controlled Substance at the federal level;

Absurd Result # 2 DUI Antidepressant

Wellbutrin is a substituted cathinone. Cathinone is a schedule I controlled substance on both the state and federal levels. Wellbutrin, a/k/a Bupropion, is an analogue of cathinone. The proposed legislation does not define the term “analogue” as used in the proposed amendments to Florida Statute 316.193(c). The affirmative defense of “legal prescribed use” is not available for analogues of Schedule I Controlled Substances. According to the language in the proposed amendment, all individuals prescribed and taking Wellbutrin would be found guilty of DUI. If the legislation were amended to specifically exclude bupropion or define “analogue” in accordance with the Federal Analog Act 21 U.S.C. 813 then taking Wellbutrin and driving would not be illegal. Nevertheless, these amendments were never made.

Absurd Result # 3 DUI Anabolic Steroids

Professional athletes and gym rats beware! Steroids are Schedule III Controlled Substances on both the state and federal level. According to the proposed amendment, you would be convicted of DUI for taking steroids if you get caught driving a car. If you use Nandrolone Undecanoate a/k/a Deca Durabolin or “Deca”, you should be prepared to take the bus for a long time as “Deca” can be detected in your biological fluids for up to 17 or 18 months after last use.

Absurd Result # 4 DUI Testicles

Adult males naturally produce testosterone. Accordingly, all men will have a certain level of testosterone in their system. Testosterone is a Schedule III controlled substance and the amendment proposed by Senator Wise made no distinction between endogenous testosterone production as opposed to “supplementing” your natural testosterone levels with external sources. All men with healthy, functioning testicles have testosterone in their system 100% of the time. Accordingly, a strict construction of the proposed amendment would result in all men with functioning testicles being guilty of DUI whenever they get behind the wheel of a car.

Absurd Result # 5 DUI’s for Everybody

It also bears mentioning that, on the average, women naturally produce testosterone at around 1/7 the rate of men. Accordingly, all normal healthy women will have some testosterone in their system 100% of the time. Since the amendment made no distinction between endogenous testosterone or illegally obtained testosterone, all normal, healthy women would be guilty of DUI.

Absurd Conclusion: Anybody who operates a motor vehicle on the streets or highways of the State of Florida is guilty of DUI.

Do These Results Seem Absurd to You?

I admit that the hypotheticals #4 and #5 above are a tad on the “extreme” side. However, that is the plain language of the statute. The results are absurd. Yet, that is what is on the horizon. Approximately 1/3 of all states have passed per se DUI statutes. These statutes are written in such a way as to criminalize innocent and socially acceptable conduct. Different states have enacted different versions of per se statutes and some drugged driving laws are better than others. For example, some states exclude specific commonly abused illegal drugs. Some limit the specimens that can be collected (urine, oral fluid, blood) or specify specific cut-off levels.

The Solution is Education

Educating younger drivers on the dangers of drugged driving is only 1/2 of the equation. However, there will be no meaningful change until the law makers educate themselves. The proposed legislation that I listed above shows exactly how out of touch politicians are with the problems faced in today’s society. How does criminalizing driving with high testosterone levels help society? There will be no change until the law makers can accurately identify the problem.

Accordingly, I stand by my conclusion. The legislature will attempt to fix a problem which they cannot identify by proposing more dumb laws. Unfortunately, sometimes those dumb ideas pass and become law.

My Offer

If any member of the Florida Legislature reads this and would like my assistance drafting a tough, effective and reasonable drugged driving statute, contact me and I will help you draft it from A to Z.

For additional information, please contact

The Law Offices of Michael A. Dye, PA, 1 East Broward Boulevard #700, Fort Lauderdale, FL 33301 (954)990-0525 or
The Law Offices of Michael A. Dye, PA, 2 S Biscayne Blvd, Miami, FL 33131 (305)459-3286

What is Flakka? | The Truth About A-PVP